Execution Chart

We display below the execution chart for this examination (boot time has been removed).

Trace from the execution

Formatting '/data/fkordon/mcc2023-input.r225-tall-167856407900639.qcow2', fmt=qcow2 size=4294967296 backing_file=/data/fkordon/mcc2023-input.qcow2 cluster_size=65536 lazy_refcounts=off refcount_bits=16
Waiting for the VM to be ready (probing ssh)
.........................................................
=====================================================================
Generated by BenchKit 2-5348
Executing tool marcie
Input is MAPKbis-PT-5310, examination is ReachabilityFireability
Time confinement is 3600 seconds
Memory confinement is 16384 MBytes
Number of cores is 1
Run identifier is r225-tall-167856407900639
=====================================================================

--------------------
preparation of the directory to be used:
/home/mcc/execution
total 636K
-rw-r--r-- 1 mcc users 6.4K Feb 25 16:17 CTLCardinality.txt
-rw-r--r-- 1 mcc users 54K Feb 25 16:17 CTLCardinality.xml
-rw-r--r-- 1 mcc users 11K Feb 25 15:59 CTLFireability.txt
-rw-r--r-- 1 mcc users 48K Feb 25 15:59 CTLFireability.xml
-rw-r--r-- 1 mcc users 4.2K Jan 29 11:40 GenericPropertiesDefinition.xml
-rw-r--r-- 1 mcc users 6.4K Jan 29 11:40 GenericPropertiesVerdict.xml
-rw-r--r-- 1 mcc users 4.2K Feb 25 16:22 LTLCardinality.txt
-rw-r--r-- 1 mcc users 26K Feb 25 16:22 LTLCardinality.xml
-rw-r--r-- 1 mcc users 6.0K Feb 25 16:22 LTLFireability.txt
-rw-r--r-- 1 mcc users 21K Feb 25 16:22 LTLFireability.xml
-rw-r--r-- 1 mcc users 13K Feb 25 16:35 ReachabilityCardinality.txt
-rw-r--r-- 1 mcc users 111K Feb 25 16:35 ReachabilityCardinality.xml
-rw-r--r-- 1 mcc users 22K Feb 25 16:26 ReachabilityFireability.txt
-rw-r--r-- 1 mcc users 82K Feb 25 16:26 ReachabilityFireability.xml
-rw-r--r-- 1 mcc users 1.7K Feb 25 16:22 UpperBounds.txt
-rw-r--r-- 1 mcc users 3.8K Feb 25 16:22 UpperBounds.xml
-rw-r--r-- 1 mcc users 6 Mar 5 18:22 equiv_col
-rw-r--r-- 1 mcc users 5 Mar 5 18:22 instance
-rw-r--r-- 1 mcc users 6 Mar 5 18:22 iscolored
-rw-r--r-- 1 mcc users 170K Mar 5 18:22 model.pnml

--------------------
content from stdout:

=== Data for post analysis generated by BenchKit (invocation template)

The expected result is a vector of booleans
BOOL_VECTOR

here is the order used to build the result vector(from text file)
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-00
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-01
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-02
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-03
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-04
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-05
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-06
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-07
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-08
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-09
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-10
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-11
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-12
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-13
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-14
FORMULA_NAME MAPKbis-PT-5310-ReachabilityFireability-15

=== Now, execution of the tool begins

BK_START 1678641216825

bash -c /home/mcc/BenchKit/BenchKit_head.sh 2> STDERR ; echo ; echo -n "BK_STOP " ; date -u +%s%3N
Invoking MCC driver with
BK_TOOL=marcie
BK_EXAMINATION=ReachabilityFireability
BK_BIN_PATH=/home/mcc/BenchKit/bin/
BK_TIME_CONFINEMENT=3600
BK_INPUT=MAPKbis-PT-5310
Not applying reductions.
Model is PT
ReachabilityFireability PT
timeout --kill-after=10s --signal=SIGINT 1m for testing only

Marcie built on Linux at 2019-11-18.
A model checker for Generalized Stochastic Petri nets

authors: Alex Tovchigrechko (IDD package and CTL model checking)

Martin Schwarick (Symbolic numerical analysis and CSL model checking)

Christian Rohr (Simulative and approximative numerical model checking)

marcie@informatik.tu-cottbus.de

called as: /home/mcc/BenchKit/bin//../marcie/bin/marcie --net-file=model.pnml --mcc-file=ReachabilityFireability.xml --memory=6 --mcc-mode

parse successfull
net created successfully

Net: MAPKbis_PT_5310
(NrP: 106 NrTr: 173 NrArc: 986)

parse formulas
formulas created successfully
place and transition orderings generation:0m 0.002sec

net check time: 0m 0.000sec

init dd package: 0m 2.891sec


RS generation: 0m 0.867sec


-> reachability set: #nodes 395 (4.0e+02) #states 3,846,411,649,024 (12)



starting MCC model checker
--------------------------

checking: AG [~ [IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_ERK_equals_1]]]
normalized: ~ [E [true U IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_ERK_equals_1]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-02 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.160sec

checking: AG [~ [IS_FIREABLE [p21_equals_1_to_p21_equals_0_when_AKT_equals_1]]]
normalized: ~ [E [true U IS_FIREABLE [p21_equals_1_to_p21_equals_0_when_AKT_equals_1]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-07 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.095sec

checking: AG [~ [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_1_and_TAOK_equals_1]]]
normalized: ~ [E [true U IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_1_and_TAOK_equals_1]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-09 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.001sec

checking: EF [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1]]
normalized: E [true U IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-14 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.052sec

checking: EF [[~ [IS_FIREABLE [PKC_equals_1_to_PKC_equals_0_when_PLCG_equals_0]] & IS_FIREABLE [TAK1_equals_0_to_TAK1_equals_1_when_TGFBR_equals_1]]]
normalized: E [true U [IS_FIREABLE [TAK1_equals_0_to_TAK1_equals_1_when_TGFBR_equals_1] & ~ [IS_FIREABLE [PKC_equals_1_to_PKC_equals_0_when_PLCG_equals_0]]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-04 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.000sec

checking: AG [[~ [IS_FIREABLE [p70_equals_0_to_p70_equals_1_when_ERK_equals_1_and_PDK1_equals_1]] | ~ [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1]]]]
normalized: ~ [E [true U ~ [[~ [IS_FIREABLE [p70_equals_0_to_p70_equals_1_when_ERK_equals_1_and_PDK1_equals_1]] | ~ [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1]]]]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-11 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.088sec

checking: AG [[[IS_FIREABLE [DUSP1_equals_0_to_DUSP1_equals_1_when_CREB_equals_1] | ~ [[IS_FIREABLE [SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0] & IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_BCL2_equals_1]]]] | ~ [[~ [IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0]] & IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1]]]]]
normalized: ~ [E [true U ~ [[~ [[IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1] & ~ [IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0]]]] | [IS_FIREABLE [DUSP1_equals_0_to_DUSP1_equals_1_when_CREB_equals_1] | ~ [[IS_FIREABLE [SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0] & IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_BCL2_equals_1]]]]]]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-15 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.000sec

checking: AG [[[[~ [IS_FIREABLE [PTEN_equals_1_to_PTEN_equals_0_when_p53_equals_0]] | [IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_0_and_TAOK_equals_0] | ~ [IS_FIREABLE [TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0]]]] | [[IS_FIREABLE [TGFBR_equals_0_to_TGFBR_equals_1_when_TGFBR_stimulus_equals_1] | IS_FIREABLE [MAX_equals_0_to_MAX_equals_1_when_p38_equals_1]] & ~ [IS_FIREABLE [MYC_equals_0_to_MYC_equals_1_when_AKT_equals_1_and_MSK_equals_1]]]] | IS_FIREABLE [RAS_equals_0_to_RAS_equals_1_when_SOS_equals_1]]]
normalized: ~ [E [true U ~ [[IS_FIREABLE [RAS_equals_0_to_RAS_equals_1_when_SOS_equals_1] | [[[IS_FIREABLE [TGFBR_equals_0_to_TGFBR_equals_1_when_TGFBR_stimulus_equals_1] | IS_FIREABLE [MAX_equals_0_to_MAX_equals_1_when_p38_equals_1]] & ~ [IS_FIREABLE [MYC_equals_0_to_MYC_equals_1_when_AKT_equals_1_and_MSK_equals_1]]] | [[IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_0_and_TAOK_equals_0] | ~ [IS_FIREABLE [TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0]]] | ~ [IS_FIREABLE [PTEN_equals_1_to_PTEN_equals_0_when_p53_equals_0]]]]]]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-06 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.001sec

checking: EF [[[IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_EGFR_equals_1] | [~ [IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PDK1_equals_0]] | [[[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1] & [[~ [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0]] | ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1]]] | ~ [IS_FIREABLE [TAK1_equals_0_to_TAK1_equals_1_when_TGFBR_equals_1]]]] | ~ [[IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0] & [[IS_FIREABLE [RAF_equals_1_to_RAF_equals_0_when_PKC_equals_0_and_RAS_equals_0] | IS_FIREABLE [PI3K_equals_0_to_PI3K_equals_1_when_GAB1_equals_1]] | [IS_FIREABLE [MAP3K1_3_equals_0_to_MAP3K1_3_equals_1_when_RAS_equals_1] & IS_FIREABLE [MAP3K1_3_equals_1_to_MAP3K1_3_equals_0_when_RAS_equals_0]]]]]] | [~ [IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_p38_equals_1]] | ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1]]]]]] & IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_1_and_TAOK_equals_1]]]
normalized: E [true U [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_1_and_TAOK_equals_1] & [IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_EGFR_equals_1] | [[[~ [IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_p38_equals_1]] | ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1]]] | [~ [[IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0] & [[IS_FIREABLE [MAP3K1_3_equals_0_to_MAP3K1_3_equals_1_when_RAS_equals_1] & IS_FIREABLE [MAP3K1_3_equals_1_to_MAP3K1_3_equals_0_when_RAS_equals_0]] | [IS_FIREABLE [RAF_equals_1_to_RAF_equals_0_when_PKC_equals_0_and_RAS_equals_0] | IS_FIREABLE [PI3K_equals_0_to_PI3K_equals_1_when_GAB1_equals_1]]]]] | [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1] & [~ [IS_FIREABLE [TAK1_equals_0_to_TAK1_equals_1_when_TGFBR_equals_1]] | [~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1]] | ~ [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0]]]]]]] | ~ [IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PDK1_equals_0]]]]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-12 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.002sec

checking: AG [[[~ [IS_FIREABLE [AP1_equals_0_to_AP1_equals_1_when_ATF2_equals_0_and_FOS_equals_1_and_JUN_equals_1]] & [[[[IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_PKC_equals_1] & IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAOK_equals_0]] & ~ [IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0]]] | [[[[[IS_FIREABLE [RAF_equals_1_to_RAF_equals_0_when_PKC_equals_0_and_RAS_equals_0] & IS_FIREABLE [PDK1_equals_1_to_PDK1_equals_0_when_PI3K_equals_0]] & IS_FIREABLE [p21_equals_1_to_p21_equals_0_when_p53_equals_0]] | [[IS_FIREABLE [MYC_equals_0_to_MYC_equals_1_when_AKT_equals_1_and_MSK_equals_1] & IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_GRB2_equals_1]] | ~ [IS_FIREABLE [AP1_equals_0_to_AP1_equals_1_when_ATF2_equals_0_and_FOS_equals_1_and_JUN_equals_1]]]] & IS_FIREABLE [p14_equals_1_to_p14_equals_0_when_MYC_equals_0]] & IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_JNK_equals_1]]] & ~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1] | [~ [[[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1] | IS_FIREABLE [ATF2_equals_1_to_ATF2_equals_0_when_JNK_equals_0_and_p38_equals_0]] & ~ [IS_FIREABLE [PPP2CA_equals_0_to_PPP2CA_equals_1_when_p38_equals_1]]]] | ~ [IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PTEN_equals_1]]]]]]] | ~ [[IS_FIREABLE [RSK_equals_1_to_RSK_equals_0_when_ERK_equals_0] & IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0]]]]]
normalized: ~ [E [true U ~ [[~ [[IS_FIREABLE [RSK_equals_1_to_RSK_equals_0_when_ERK_equals_0] & IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0]]] | [[~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1] | [~ [IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PTEN_equals_1]] | ~ [[~ [IS_FIREABLE [PPP2CA_equals_0_to_PPP2CA_equals_1_when_p38_equals_1]] & [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1] | IS_FIREABLE [ATF2_equals_1_to_ATF2_equals_0_when_JNK_equals_0_and_p38_equals_0]]]]]]] & [[IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_JNK_equals_1] & [IS_FIREABLE [p14_equals_1_to_p14_equals_0_when_MYC_equals_0] & [[~ [IS_FIREABLE [AP1_equals_0_to_AP1_equals_1_when_ATF2_equals_0_and_FOS_equals_1_and_JUN_equals_1]] | [IS_FIREABLE [MYC_equals_0_to_MYC_equals_1_when_AKT_equals_1_and_MSK_equals_1] & IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_GRB2_equals_1]]] | [IS_FIREABLE [p21_equals_1_to_p21_equals_0_when_p53_equals_0] & [IS_FIREABLE [RAF_equals_1_to_RAF_equals_0_when_PKC_equals_0_and_RAS_equals_0] & IS_FIREABLE [PDK1_equals_1_to_PDK1_equals_0_when_PI3K_equals_0]]]]]] | [~ [IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0]] & [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_PKC_equals_1] & IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAOK_equals_0]]]]] & ~ [IS_FIREABLE [AP1_equals_0_to_AP1_equals_1_when_ATF2_equals_0_and_FOS_equals_1_and_JUN_equals_1]]]]]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-01 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.076sec

checking: AG [[[[~ [[[[IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0] | [[IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_FGFR3_equals_0] | IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0]] | [IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0] & IS_FIREABLE [p21_equals_0_to_p21_equals_1_when_AKT_equals_0_and_p53_equals_1]]]] & IS_FIREABLE [RAS_equals_0_to_RAS_equals_1_when_PLCG_equals_1]] & IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1]]] | IS_FIREABLE [PLCG_equals_0_to_PLCG_equals_1_when_EGFR_equals_1]] & [[IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PTEN_equals_1] | ~ [[IS_FIREABLE [PDK1_equals_0_to_PDK1_equals_1_when_PI3K_equals_1] & IS_FIREABLE [Proliferation_equals_1_to_Proliferation_equals_0_when_MYC_equals_0]]]] | IS_FIREABLE [p70_equals_0_to_p70_equals_1_when_ERK_equals_1_and_PDK1_equals_1]]] | ~ [[~ [[[IS_FIREABLE [FOS_equals_1_to_FOS_equals_0_when_RSK_equals_0] | ~ [IS_FIREABLE [RAF_equals_1_to_RAF_equals_0_when_PKC_equals_0_and_RAS_equals_0]]] & IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0]]] | [[~ [[~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]] & IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]]] & IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_GRB2_equals_1]] | ~ [IS_FIREABLE [BCL2_equals_1_to_BCL2_equals_0_when_CREB_equals_0]]]]]]]
normalized: ~ [E [true U ~ [[~ [[[~ [IS_FIREABLE [BCL2_equals_1_to_BCL2_equals_0_when_CREB_equals_0]] | [IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_GRB2_equals_1] & ~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1] & ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]]]]]] | ~ [[IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0] & [IS_FIREABLE [FOS_equals_1_to_FOS_equals_0_when_RSK_equals_0] | ~ [IS_FIREABLE [RAF_equals_1_to_RAF_equals_0_when_PKC_equals_0_and_RAS_equals_0]]]]]]] | [[IS_FIREABLE [p70_equals_0_to_p70_equals_1_when_ERK_equals_1_and_PDK1_equals_1] | [IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PTEN_equals_1] | ~ [[IS_FIREABLE [PDK1_equals_0_to_PDK1_equals_1_when_PI3K_equals_1] & IS_FIREABLE [Proliferation_equals_1_to_Proliferation_equals_0_when_MYC_equals_0]]]]] & [IS_FIREABLE [PLCG_equals_0_to_PLCG_equals_1_when_EGFR_equals_1] | ~ [[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1] & [IS_FIREABLE [RAS_equals_0_to_RAS_equals_1_when_PLCG_equals_1] & [IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0] | [[IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0] & IS_FIREABLE [p21_equals_0_to_p21_equals_1_when_AKT_equals_0_and_p53_equals_1]] | [IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_FGFR3_equals_0] | IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0]]]]]]]]]]]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-03 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.522sec

checking: AG [~ [[[[~ [[~ [[[IS_FIREABLE [GADD45_equals_1_to_GADD45_equals_0_when_SMAD_equals_0_and_p53_equals_0] | IS_FIREABLE [MYC_equals_1_to_MYC_equals_0_when_MSK_equals_0]] & ~ [IS_FIREABLE [MDM2_equals_1_to_MDM2_equals_0_when_p14_equals_1]]]] | IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0]]] & [IS_FIREABLE [RSK_equals_1_to_RSK_equals_0_when_ERK_equals_0] & IS_FIREABLE [p53_equals_0_to_p53_equals_1_when_ATM_equals_1_and_p38_equals_1]]] & [[[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_1] | [[~ [IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_GRB2_equals_1]] | [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0] | IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_EGFR_equals_1]]] & ~ [[IS_FIREABLE [Apoptosis_equals_0_to_Apoptosis_equals_1_when_BCL2_equals_0_and_ERK_equals_0_and_FOXO3_equals_1_and_p53_equals_1] | IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0]]]]] & ~ [[[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_RSK_equals_1] & [IS_FIREABLE [MSK_equals_1_to_MSK_equals_0_when_ERK_equals_0_and_p38_equals_0] & IS_FIREABLE [TGFBR_equals_1_to_TGFBR_equals_0_when_TGFBR_stimulus_equals_0]]] & ~ [IS_FIREABLE [ATF2_equals_1_to_ATF2_equals_0_when_JNK_equals_0_and_p38_equals_0]]]]] | [IS_FIREABLE [FGFR3_equals_1_to_FGFR3_equals_0_when_GRB2_equals_1] | IS_FIREABLE [DUSP1_equals_1_to_DUSP1_equals_0_when_CREB_equals_0]]]] & IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0]]]]
normalized: ~ [E [true U [IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0] & [[[IS_FIREABLE [FGFR3_equals_1_to_FGFR3_equals_0_when_GRB2_equals_1] | IS_FIREABLE [DUSP1_equals_1_to_DUSP1_equals_0_when_CREB_equals_0]] | [~ [[~ [IS_FIREABLE [ATF2_equals_1_to_ATF2_equals_0_when_JNK_equals_0_and_p38_equals_0]] & [IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_RSK_equals_1] & [IS_FIREABLE [MSK_equals_1_to_MSK_equals_0_when_ERK_equals_0_and_p38_equals_0] & IS_FIREABLE [TGFBR_equals_1_to_TGFBR_equals_0_when_TGFBR_stimulus_equals_0]]]]] & [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_1] | [~ [[IS_FIREABLE [Apoptosis_equals_0_to_Apoptosis_equals_1_when_BCL2_equals_0_and_ERK_equals_0_and_FOXO3_equals_1_and_p53_equals_1] | IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0]]] & [[IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0] | IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_EGFR_equals_1]] | ~ [IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_GRB2_equals_1]]]]]]] & [[IS_FIREABLE [RSK_equals_1_to_RSK_equals_0_when_ERK_equals_0] & IS_FIREABLE [p53_equals_0_to_p53_equals_1_when_ATM_equals_1_and_p38_equals_1]] & ~ [[IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0] | ~ [[~ [IS_FIREABLE [MDM2_equals_1_to_MDM2_equals_0_when_p14_equals_1]] & [IS_FIREABLE [GADD45_equals_1_to_GADD45_equals_0_when_SMAD_equals_0_and_p53_equals_0] | IS_FIREABLE [MYC_equals_1_to_MYC_equals_0_when_MSK_equals_0]]]]]]]]]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-10 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.002sec

checking: AG [[[[[IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0] & ~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1] & [IS_FIREABLE [MAP3K1_3_equals_0_to_MAP3K1_3_equals_1_when_RAS_equals_1] & ~ [IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1]]]]]] | ~ [IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_TGFBR_equals_1]]] | [[[[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAOK_equals_1] | [[[IS_FIREABLE [p14_equals_0_to_p14_equals_1_when_MYC_equals_1] | IS_FIREABLE [ATM_equals_0_to_ATM_equals_1_when_DNA_damage_equals_1]] | ~ [IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0]]] & [~ [IS_FIREABLE [FOS_equals_1_to_FOS_equals_0_when_RSK_equals_0]] & IS_FIREABLE [MDM2_equals_1_to_MDM2_equals_0_when_AKT_equals_0_and_p53_equals_0]]]] | [[~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1] & IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1]]] | IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1]] | [~ [[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_0_and_p38_equals_0] | IS_FIREABLE [JUN_equals_1_to_JUN_equals_0_when_JNK_equals_0]]] | [[IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0] & IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_p38_equals_1]] & [IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_0_and_TAOK_equals_0] | IS_FIREABLE [p21_equals_0_to_p21_equals_1_when_AKT_equals_0_and_p53_equals_1]]]]]] & IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_MAP3K1_3_equals_1]] | IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1]]] | ~ [[[~ [IS_FIREABLE [MDM2_equals_0_to_MDM2_equals_1_when_AKT_equals_0_and_p14_equals_0_and_p53_equals_1]] | IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PTEN_equals_1]] & ~ [[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_0_and_MDM2_equals_1] & IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_0_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0]]]]]]]
normalized: ~ [E [true U ~ [[~ [[~ [[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_0_and_MDM2_equals_1] & IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_0_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0]]] & [IS_FIREABLE [AKT_equals_1_to_AKT_equals_0_when_PTEN_equals_1] | ~ [IS_FIREABLE [MDM2_equals_0_to_MDM2_equals_1_when_AKT_equals_0_and_p14_equals_0_and_p53_equals_1]]]]] | [[IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1] | [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_MAP3K1_3_equals_1] & [[[[[IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_0_and_TAOK_equals_0] | IS_FIREABLE [p21_equals_0_to_p21_equals_1_when_AKT_equals_0_and_p53_equals_1]] & [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0] & IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_p38_equals_1]]] | ~ [[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_0_and_p38_equals_0] | IS_FIREABLE [JUN_equals_1_to_JUN_equals_0_when_JNK_equals_0]]]] | [IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1] | ~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1] & IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1]]]]] | [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAOK_equals_1] | [[IS_FIREABLE [MDM2_equals_1_to_MDM2_equals_0_when_AKT_equals_0_and_p53_equals_0] & ~ [IS_FIREABLE [FOS_equals_1_to_FOS_equals_0_when_RSK_equals_0]]] & [~ [IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0]] | [IS_FIREABLE [p14_equals_0_to_p14_equals_1_when_MYC_equals_1] | IS_FIREABLE [ATM_equals_0_to_ATM_equals_1_when_DNA_damage_equals_1]]]]]]]] | [~ [IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_TGFBR_equals_1]] | [IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0] & ~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1] & [IS_FIREABLE [MAP3K1_3_equals_0_to_MAP3K1_3_equals_1_when_RAS_equals_1] & ~ [IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1]]]]]]]]]]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-13 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.003sec

checking: AG [~ [[~ [[[~ [[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1] | IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1]]] & [~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]] | [IS_FIREABLE [MSK_equals_0_to_MSK_equals_1_when_ERK_equals_1] | IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0]]]] & [[[IS_FIREABLE [AP1_equals_1_to_AP1_equals_0_when_JUN_equals_0] & IS_FIREABLE [MSK_equals_0_to_MSK_equals_1_when_p38_equals_1]] & [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_PKC_equals_1] & IS_FIREABLE [PTEN_equals_1_to_PTEN_equals_0_when_p53_equals_0]]] | ~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1] | IS_FIREABLE [TAK1_equals_1_to_TAK1_equals_0_when_TGFBR_equals_0]]]]]] & ~ [[[~ [[IS_FIREABLE [AP1_equals_1_to_AP1_equals_0_when_ATF2_equals_0_and_FOS_equals_0] & IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]]] & IS_FIREABLE [Growth_Arrest_equals_1_to_Growth_Arrest_equals_0_when_p21_equals_0]] | [[~ [[[IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_0_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0] | IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]] | [IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_0_and_p38_equals_0] | IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAOK_equals_0]]]] & [[[IS_FIREABLE [MYC_equals_1_to_MYC_equals_0_when_AKT_equals_0_and_MAX_equals_0] & IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0]] & IS_FIREABLE [DUSP1_equals_0_to_DUSP1_equals_1_when_CREB_equals_1]] & [[IS_FIREABLE [MAX_equals_0_to_MAX_equals_1_when_p38_equals_1] | IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_JNK_equals_1]] | IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1]]]] | [[[IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0] | [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_GRB2_equals_1] & IS_FIREABLE [GADD45_equals_0_to_GADD45_equals_1_when_p53_equals_1]]] & ~ [[IS_FIREABLE [p14_equals_0_to_p14_equals_1_when_MYC_equals_1] | IS_FIREABLE [JUN_equals_0_to_JUN_equals_1_when_JNK_equals_1]]]] | ~ [IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_PI3K_equals_1]]]]]]]]]
normalized: ~ [E [true U [~ [[[[~ [IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_PI3K_equals_1]] | [~ [[IS_FIREABLE [p14_equals_0_to_p14_equals_1_when_MYC_equals_1] | IS_FIREABLE [JUN_equals_0_to_JUN_equals_1_when_JNK_equals_1]]] & [IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0] | [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_GRB2_equals_1] & IS_FIREABLE [GADD45_equals_0_to_GADD45_equals_1_when_p53_equals_1]]]]] | [[[IS_FIREABLE [ERK_equals_0_to_ERK_equals_1_when_MEK1_2_equals_1] | [IS_FIREABLE [MAX_equals_0_to_MAX_equals_1_when_p38_equals_1] | IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_JNK_equals_1]]] & [IS_FIREABLE [DUSP1_equals_0_to_DUSP1_equals_1_when_CREB_equals_1] & [IS_FIREABLE [MYC_equals_1_to_MYC_equals_0_when_AKT_equals_0_and_MAX_equals_0] & IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0]]]] & ~ [[[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_0_and_p38_equals_0] | IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAOK_equals_0]] | [IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_0_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0] | IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]]]]]] | [IS_FIREABLE [Growth_Arrest_equals_1_to_Growth_Arrest_equals_0_when_p21_equals_0] & ~ [[IS_FIREABLE [AP1_equals_1_to_AP1_equals_0_when_ATF2_equals_0_and_FOS_equals_0] & IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]]]]]] & ~ [[[~ [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1] | IS_FIREABLE [TAK1_equals_1_to_TAK1_equals_0_when_TGFBR_equals_0]]] | [[IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_PKC_equals_1] & IS_FIREABLE [PTEN_equals_1_to_PTEN_equals_0_when_p53_equals_0]] & [IS_FIREABLE [AP1_equals_1_to_AP1_equals_0_when_JUN_equals_0] & IS_FIREABLE [MSK_equals_0_to_MSK_equals_1_when_p38_equals_1]]]] & [[[IS_FIREABLE [MSK_equals_0_to_MSK_equals_1_when_ERK_equals_1] | IS_FIREABLE [ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0]] | ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]]] & ~ [[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_1] | IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1]]]]]]]]]

-> the formula is FALSE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-08 FALSE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.087sec

checking: AG [[[~ [[[[~ [IS_FIREABLE [PI3K_equals_1_to_PI3K_equals_0_when_GAB1_equals_0_and_RAS_equals_0]] & ~ [[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_GRB2_equals_0] & IS_FIREABLE [GAB1_equals_1_to_GAB1_equals_0_when_GRB2_equals_0_and_PI3K_equals_0]]]] & ~ [IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]]] | [[IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0] & ~ [IS_FIREABLE [EGFR_equals_0_to_EGFR_equals_1_when_EGFR_stimulus_equals_0_and_GRB2_equals_0_and_PKC_equals_0_and_SPRY_equals_1]]] & [~ [[IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0] & IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_GRB2_equals_1]]] | [IS_FIREABLE [BCL2_equals_0_to_BCL2_equals_1_when_AKT_equals_1_and_CREB_equals_1] | IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_JNK_equals_1]]]]]] | [[[[IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0] | IS_FIREABLE [p70_equals_1_to_p70_equals_0_when_PDK1_equals_0]] | IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0]] | [[~ [IS_FIREABLE [ERK_equals_1_to_ERK_equals_0_when_MEK1_2_equals_0]] | ~ [IS_FIREABLE [EGFR_equals_0_to_EGFR_equals_1_when_EGFR_stimulus_equals_1_and_GRB2_equals_0_and_PKC_equals_0]]] | ~ [[[IS_FIREABLE [FOXO3_equals_1_to_FOXO3_equals_0_when_AKT_equals_1] | IS_FIREABLE [FOS_equals_0_to_FOS_equals_1_when_CREB_equals_0_and_ELK1_equals_1_and_ERK_equals_1_and_RSK_equals_1]] & ~ [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0]]]]]] | IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1]]] | ~ [[[[~ [[[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_GRB2_equals_0] | IS_FIREABLE [MTK1_equals_0_to_MTK1_equals_1_when_GADD45_equals_1]] & [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_PKC_equals_1] & IS_FIREABLE [SPRY_equals_1_to_SPRY_equals_0_when_ERK_equals_0]]]] & IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]] & [IS_FIREABLE [MAP3K1_3_equals_0_to_MAP3K1_3_equals_1_when_RAS_equals_1] & ~ [[~ [IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0]] | ~ [IS_FIREABLE [FOS_equals_1_to_FOS_equals_0_when_ERK_equals_0]]]]]] & [IS_FIREABLE [MDM2_equals_0_to_MDM2_equals_1_when_AKT_equals_1_and_p14_equals_0] | ~ [[[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_RSK_equals_1] | IS_FIREABLE [BCL2_equals_0_to_BCL2_equals_1_when_AKT_equals_1_and_CREB_equals_1]] | ~ [IS_FIREABLE [PDK1_equals_0_to_PDK1_equals_1_when_PI3K_equals_1]]]]]]]]]
normalized: ~ [E [true U ~ [[~ [[[IS_FIREABLE [MDM2_equals_0_to_MDM2_equals_1_when_AKT_equals_1_and_p14_equals_0] | ~ [[[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_RSK_equals_1] | IS_FIREABLE [BCL2_equals_0_to_BCL2_equals_1_when_AKT_equals_1_and_CREB_equals_1]] | ~ [IS_FIREABLE [PDK1_equals_0_to_PDK1_equals_1_when_PI3K_equals_1]]]]] & [[IS_FIREABLE [MAP3K1_3_equals_0_to_MAP3K1_3_equals_1_when_RAS_equals_1] & ~ [[~ [IS_FIREABLE [FOS_equals_1_to_FOS_equals_0_when_ERK_equals_0]] | ~ [IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0]]]]] & [IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1] & ~ [[[IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_PKC_equals_1] & IS_FIREABLE [SPRY_equals_1_to_SPRY_equals_0_when_ERK_equals_0]] & [IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_GRB2_equals_0] | IS_FIREABLE [MTK1_equals_0_to_MTK1_equals_1_when_GADD45_equals_1]]]]]]]] | [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1] | [[~ [[~ [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0]] & [IS_FIREABLE [FOXO3_equals_1_to_FOXO3_equals_0_when_AKT_equals_1] | IS_FIREABLE [FOS_equals_0_to_FOS_equals_1_when_CREB_equals_0_and_ELK1_equals_1_and_ERK_equals_1_and_RSK_equals_1]]]] | [~ [IS_FIREABLE [EGFR_equals_0_to_EGFR_equals_1_when_EGFR_stimulus_equals_1_and_GRB2_equals_0_and_PKC_equals_0]] | ~ [IS_FIREABLE [ERK_equals_1_to_ERK_equals_0_when_MEK1_2_equals_0]]]] | [IS_FIREABLE [GRB2_equals_1_to_GRB2_equals_0_when_EGFR_equals_0_and_FRS2_equals_0_and_TGFBR_equals_0] | [IS_FIREABLE [MAX_equals_1_to_MAX_equals_0_when_p38_equals_0] | IS_FIREABLE [p70_equals_1_to_p70_equals_0_when_PDK1_equals_0]]]]] | ~ [[[[[IS_FIREABLE [BCL2_equals_0_to_BCL2_equals_1_when_AKT_equals_1_and_CREB_equals_1] | IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_JNK_equals_1]] | ~ [[IS_FIREABLE [MTK1_equals_1_to_MTK1_equals_0_when_GADD45_equals_0] & IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_GRB2_equals_1]]]] & [IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0] & ~ [IS_FIREABLE [EGFR_equals_0_to_EGFR_equals_1_when_EGFR_stimulus_equals_0_and_GRB2_equals_0_and_PKC_equals_0_and_SPRY_equals_1]]]] | [~ [IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]] & [~ [[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_GRB2_equals_0] & IS_FIREABLE [GAB1_equals_1_to_GAB1_equals_0_when_GRB2_equals_0_and_PI3K_equals_0]]] & ~ [IS_FIREABLE [PI3K_equals_1_to_PI3K_equals_0_when_GAB1_equals_0_and_RAS_equals_0]]]]]]]]]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-00 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.008sec

checking: AG [[[~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1]] & [[[[[[[IS_FIREABLE [TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0] | IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_p38_equals_1]] & IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MAP3K1_3_equals_1]] & IS_FIREABLE [PDK1_equals_0_to_PDK1_equals_1_when_PI3K_equals_1]] & ~ [[~ [IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_PI3K_equals_1]] | IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAOK_equals_1]]]] & [~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1]] & ~ [IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_JNK_equals_1]]]] | ~ [[IS_FIREABLE [PI3K_equals_1_to_PI3K_equals_0_when_GAB1_equals_0_and_RAS_equals_0] | [[IS_FIREABLE [ATM_equals_0_to_ATM_equals_1_when_DNA_damage_equals_1] & [IS_FIREABLE [SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0] | IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]]] | [[IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0] & IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_GRB2_equals_1]] | ~ [IS_FIREABLE [BCL2_equals_1_to_BCL2_equals_0_when_CREB_equals_0]]]]]]] & [IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_ERK_equals_1] | [[~ [IS_FIREABLE [SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0]] | [[~ [IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1]] | IS_FIREABLE [FOS_equals_0_to_FOS_equals_1_when_CREB_equals_0_and_ELK1_equals_1_and_ERK_equals_1_and_RSK_equals_1]] & IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAOK_equals_1]]] & [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAOK_equals_1] | IS_FIREABLE [MYC_equals_0_to_MYC_equals_1_when_AKT_equals_0_and_MAX_equals_1_and_MSK_equals_1]]]]]] | [IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0] | [[IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_RSK_equals_1] | [IS_FIREABLE [ATF2_equals_1_to_ATF2_equals_0_when_JNK_equals_0_and_p38_equals_0] | [[[~ [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_RAS_equals_1]] | [IS_FIREABLE [RSK_equals_0_to_RSK_equals_1_when_ERK_equals_1] & IS_FIREABLE [MYC_equals_1_to_MYC_equals_0_when_AKT_equals_0_and_MAX_equals_0]]] | ~ [[IS_FIREABLE [TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0] & IS_FIREABLE [FGFR3_equals_1_to_FGFR3_equals_0_when_FGFR3_stimulus_equals_0]]]] | [[~ [IS_FIREABLE [MTK1_equals_0_to_MTK1_equals_1_when_GADD45_equals_1]] & IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1]] & ~ [[IS_FIREABLE [FGFR3_equals_0_to_FGFR3_equals_1_when_FGFR3_stimulus_equals_1_and_GRB2_equals_0_and_PKC_equals_0] & IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_PKC_equals_1]]]]]]] | [[[IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_RAS_equals_1] | [~ [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1]] | ~ [[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_1_and_MDM2_equals_1_and_p38_equals_0] | IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_JNK_equals_1]]]]] | [[[~ [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_RAS_equals_1]] | [IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_BCL2_equals_1] | IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_ERK_equals_1]]] & ~ [IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_FGFR3_equals_0]]] | IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0]]] | ~ [[[IS_FIREABLE [PDK1_equals_1_to_PDK1_equals_0_when_PI3K_equals_0] & [[IS_FIREABLE [MDM2_equals_1_to_MDM2_equals_0_when_p14_equals_1] | IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_BCL2_equals_1]] | ~ [IS_FIREABLE [FRS2_equals_0_to_FRS2_equals_1_when_FGFR3_equals_1_and_GRB2_equals_0_and_SPRY_equals_0]]]] | IS_FIREABLE [p21_equals_1_to_p21_equals_0_when_p53_equals_0]]]]]]]]
normalized: ~ [E [true U ~ [[[IS_FIREABLE [JNK_equals_1_to_JNK_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_MTK1_equals_0_and_TAK1_equals_0_and_TAOK_equals_0] | [[~ [[IS_FIREABLE [p21_equals_1_to_p21_equals_0_when_p53_equals_0] | [IS_FIREABLE [PDK1_equals_1_to_PDK1_equals_0_when_PI3K_equals_0] & [[IS_FIREABLE [MDM2_equals_1_to_MDM2_equals_0_when_p14_equals_1] | IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_BCL2_equals_1]] | ~ [IS_FIREABLE [FRS2_equals_0_to_FRS2_equals_1_when_FGFR3_equals_1_and_GRB2_equals_0_and_SPRY_equals_0]]]]]] | [[IS_FIREABLE [p38_equals_1_to_p38_equals_0_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_0] | [~ [IS_FIREABLE [FRS2_equals_1_to_FRS2_equals_0_when_FGFR3_equals_0]] & [[IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_BCL2_equals_1] | IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_ERK_equals_1]] | ~ [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_RAS_equals_1]]]]] | [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_RAS_equals_1] | [~ [[IS_FIREABLE [p53_equals_1_to_p53_equals_0_when_ATM_equals_1_and_MDM2_equals_1_and_p38_equals_0] | IS_FIREABLE [ATF2_equals_0_to_ATF2_equals_1_when_JNK_equals_1]]] | ~ [IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1]]]]]] | [IS_FIREABLE [SOS_equals_1_to_SOS_equals_0_when_RSK_equals_1] | [IS_FIREABLE [ATF2_equals_1_to_ATF2_equals_0_when_JNK_equals_0_and_p38_equals_0] | [[~ [[IS_FIREABLE [TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0] & IS_FIREABLE [FGFR3_equals_1_to_FGFR3_equals_0_when_FGFR3_stimulus_equals_0]]] | [[IS_FIREABLE [RSK_equals_0_to_RSK_equals_1_when_ERK_equals_1] & IS_FIREABLE [MYC_equals_1_to_MYC_equals_0_when_AKT_equals_0_and_MAX_equals_0]] | ~ [IS_FIREABLE [RAF_equals_0_to_RAF_equals_1_when_AKT_equals_0_and_ERK_equals_0_and_RAS_equals_1]]]] | [~ [[IS_FIREABLE [FGFR3_equals_0_to_FGFR3_equals_1_when_FGFR3_stimulus_equals_1_and_GRB2_equals_0_and_PKC_equals_0] & IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_PKC_equals_1]]] & [IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1] & ~ [IS_FIREABLE [MTK1_equals_0_to_MTK1_equals_1_when_GADD45_equals_1]]]]]]]]] | [[[IS_FIREABLE [Apoptosis_equals_1_to_Apoptosis_equals_0_when_ERK_equals_1] | [[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAOK_equals_1] | IS_FIREABLE [MYC_equals_0_to_MYC_equals_1_when_AKT_equals_0_and_MAX_equals_1_and_MSK_equals_1]] & [[IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAOK_equals_1] & [IS_FIREABLE [FOS_equals_0_to_FOS_equals_1_when_CREB_equals_0_and_ELK1_equals_1_and_ERK_equals_1_and_RSK_equals_1] | ~ [IS_FIREABLE [GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1]]]] | ~ [IS_FIREABLE [SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0]]]]] & [~ [[IS_FIREABLE [PI3K_equals_1_to_PI3K_equals_0_when_GAB1_equals_0_and_RAS_equals_0] | [[~ [IS_FIREABLE [BCL2_equals_1_to_BCL2_equals_0_when_CREB_equals_0]] | [IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0] & IS_FIREABLE [EGFR_equals_1_to_EGFR_equals_0_when_GRB2_equals_1]]] | [IS_FIREABLE [ATM_equals_0_to_ATM_equals_1_when_DNA_damage_equals_1] & [IS_FIREABLE [SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0] | IS_FIREABLE [SPRY_equals_0_to_SPRY_equals_1_when_ERK_equals_1]]]]]] | [[~ [IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_JNK_equals_1]] & ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1]]] & [~ [[IS_FIREABLE [JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAOK_equals_1] | ~ [IS_FIREABLE [GAB1_equals_0_to_GAB1_equals_1_when_PI3K_equals_1]]]] & [IS_FIREABLE [PDK1_equals_0_to_PDK1_equals_1_when_PI3K_equals_1] & [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MAP3K1_3_equals_1] & [IS_FIREABLE [TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0] | IS_FIREABLE [ELK1_equals_0_to_ELK1_equals_1_when_p38_equals_1]]]]]]]] & ~ [IS_FIREABLE [p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_MTK1_equals_1]]]]]]]

-> the formula is TRUE

FORMULA MAPKbis-PT-5310-ReachabilityFireability-05 TRUE TECHNIQUES SEQUENTIAL_PROCESSING DECISION_DIAGRAMS UNFOLDING_TO_PT

MC time: 0m 0.003sec

totally nodes used: 744783 (7.4e+05)
number of garbage collections: 0
fire ops cache: hits/miss/sum: 2214556 6652288 8866844
used/not used/entry size/cache size: 7010877 60097987 16 1024MB
basic ops cache: hits/miss/sum: 212554 540406 752960
used/not used/entry size/cache size: 1024662 15752554 12 192MB
unary ops cache: hits/miss/sum: 0 0 0
used/not used/entry size/cache size: 0 16777216 8 128MB
abstract ops cache: hits/miss/sum: 0 0 0
used/not used/entry size/cache size: 0 16777216 12 192MB
state nr cache: hits/miss/sum: 123 395 518
used/not used/entry size/cache size: 395 8388213 32 256MB
max state cache: hits/miss/sum: 0 0 0
used/not used/entry size/cache size: 0 8388608 32 256MB
uniqueHash elements/entry size/size: 67108864 4 256MB
0 66388476
1 697517
2 21427
3 1365
4 78
5 1
6 0
7 0
8 0
9 0
>= 10 0

Total processing time: 0m 6.649sec


BK_STOP 1678641223522

--------------------
content from stderr:

check for maximal unmarked siphon
found
The net has a maximal unmarked siphon:
SMAD_equals_1
ATM_equals_1
TAK1_equals_1
TAOK_equals_1
TGFBR_equals_1
TGFBR_stimulus_equals_1
FRS2_equals_1
EGFR_stimulus_equals_0
FGFR3_equals_1
FGFR3_stimulus_equals_1
DNA_damage_equals_1

The net has transition(s) that can never fire:
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_1_and_TAOK_equals_1
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_1
GADD45_equals_0_to_GADD45_equals_1_when_SMAD_equals_1
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAOK_equals_1
GRB2_equals_0_to_GRB2_equals_1_when_FRS2_equals_1
GRB2_equals_0_to_GRB2_equals_1_when_TGFBR_equals_1
p53_equals_1_to_p53_equals_0_when_ATM_equals_1_and_MDM2_equals_1_and_p38_equals_0
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAOK_equals_1
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1
p53_equals_0_to_p53_equals_1_when_ATM_equals_1_and_MDM2_equals_0
p53_equals_0_to_p53_equals_1_when_ATM_equals_1_and_p38_equals_1
PLCG_equals_0_to_PLCG_equals_1_when_FGFR3_equals_1
TAK1_equals_0_to_TAK1_equals_1_when_TGFBR_equals_1
TAK1_equals_1_to_TAK1_equals_0_when_TGFBR_equals_0
TAOK_equals_0_to_TAOK_equals_1_when_ATM_equals_1
TAOK_equals_1_to_TAOK_equals_0_when_ATM_equals_0
TGFBR_equals_0_to_TGFBR_equals_1_when_TGFBR_stimulus_equals_1
TGFBR_equals_1_to_TGFBR_equals_0_when_TGFBR_stimulus_equals_0
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_0_and_TAOK_equals_1
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_0_and_TAK1_equals_1_and_TAOK_equals_1
p38_equals_0_to_p38_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_0_and_MTK1_equals_1_and_TAK1_equals_1
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAK1_equals_1
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_0_and_TAOK_equals_1
SMAD_equals_0_to_SMAD_equals_1_when_TGFBR_equals_1
SMAD_equals_1_to_SMAD_equals_0_when_TGFBR_equals_0
FGFR3_equals_0_to_FGFR3_equals_1_when_FGFR3_stimulus_equals_1_and_GRB2_equals_0_and_PKC_equals_0
FGFR3_equals_1_to_FGFR3_equals_0_when_FGFR3_stimulus_equals_0
FGFR3_equals_1_to_FGFR3_equals_0_when_GRB2_equals_1
FGFR3_equals_1_to_FGFR3_equals_0_when_PKC_equals_1
FRS2_equals_1_to_FRS2_equals_0_when_GRB2_equals_1
FRS2_equals_1_to_FRS2_equals_0_when_SPRY_equals_1
EGFR_equals_0_to_EGFR_equals_1_when_EGFR_stimulus_equals_0_and_GRB2_equals_0_and_PKC_equals_0_and_SPRY_equals_1
ATM_equals_0_to_ATM_equals_1_when_DNA_damage_equals_1
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAK1_equals_1
JNK_equals_0_to_JNK_equals_1_when_DUSP1_equals_1_and_MAP3K1_3_equals_1_and_TAOK_equals_1
FRS2_equals_0_to_FRS2_equals_1_when_FGFR3_equals_1_and_GRB2_equals_0_and_SPRY_equals_0
FRS2_equals_1_to_FRS2_equals_0_when_FGFR3_equals_0
ATM_equals_1_to_ATM_equals_0_when_DNA_damage_equals_0
EGFR_equals_1_to_EGFR_equals_0_when_EGFR_stimulus_equals_0_and_SPRY_equals_0

check for constant places
DNA_damage_equals_0
DNA_damage_equals_1
EGFR_stimulus_equals_0
EGFR_stimulus_equals_1
FGFR3_stimulus_equals_0
FGFR3_stimulus_equals_1
TGFBR_stimulus_equals_0
TGFBR_stimulus_equals_1
found 8 constant places
check if there are places and transitions
ok
check if there are transitions without pre-places
ok
check if at least one transition is enabled in m0
ok
check if there are transitions that can never fire
ok


initing FirstDep: 0m 0.002sec


iterations count:21457 (124), effective:1545 (8)

initing FirstDep: 0m 0.000sec


iterations count:4066 (23), effective:184 (1)

iterations count:2824 (16), effective:139 (0)

iterations count:2471 (14), effective:108 (0)

iterations count:4056 (23), effective:193 (1)

iterations count:3694 (21), effective:164 (0)

iterations count:7115 (41), effective:439 (2)

iterations count:3441 (19), effective:166 (0)

Sequence of Actions to be Executed by the VM

This is useful if one wants to reexecute the tool in the VM from the submitted image disk.

set -x
# this is for BenchKit: configuration of major elements for the test
export BK_INPUT="MAPKbis-PT-5310"
export BK_EXAMINATION="ReachabilityFireability"
export BK_TOOL="marcie"
export BK_RESULT_DIR="/tmp/BK_RESULTS/OUTPUTS"
export BK_TIME_CONFINEMENT="3600"
export BK_MEMORY_CONFINEMENT="16384"
export BK_BIN_PATH="/home/mcc/BenchKit/bin/"

# this is specific to your benchmark or test

export BIN_DIR="$HOME/BenchKit/bin"

# remove the execution directoty if it exists (to avoid increse of .vmdk images)
if [ -d execution ] ; then
rm -rf execution
fi

# this is for BenchKit: explicit launching of the test
echo "====================================================================="
echo " Generated by BenchKit 2-5348"
echo " Executing tool marcie"
echo " Input is MAPKbis-PT-5310, examination is ReachabilityFireability"
echo " Time confinement is $BK_TIME_CONFINEMENT seconds"
echo " Memory confinement is 16384 MBytes"
echo " Number of cores is 1"
echo " Run identifier is r225-tall-167856407900639"
echo "====================================================================="
echo
echo "--------------------"
echo "preparation of the directory to be used:"

tar xzf /home/mcc/BenchKit/INPUTS/MAPKbis-PT-5310.tgz
mv MAPKbis-PT-5310 execution
cd execution
if [ "ReachabilityFireability" = "ReachabilityDeadlock" ] || [ "ReachabilityFireability" = "UpperBounds" ] || [ "ReachabilityFireability" = "QuasiLiveness" ] || [ "ReachabilityFireability" = "StableMarking" ] || [ "ReachabilityFireability" = "Liveness" ] || [ "ReachabilityFireability" = "OneSafe" ] || [ "ReachabilityFireability" = "StateSpace" ]; then
rm -f GenericPropertiesVerdict.xml
fi
pwd
ls -lh

echo
echo "--------------------"
echo "content from stdout:"
echo
echo "=== Data for post analysis generated by BenchKit (invocation template)"
echo
if [ "ReachabilityFireability" = "UpperBounds" ] ; then
echo "The expected result is a vector of positive values"
echo NUM_VECTOR
elif [ "ReachabilityFireability" != "StateSpace" ] ; then
echo "The expected result is a vector of booleans"
echo BOOL_VECTOR
else
echo "no data necessary for post analysis"
fi
echo
if [ -f "ReachabilityFireability.txt" ] ; then
echo "here is the order used to build the result vector(from text file)"
for x in $(grep Property ReachabilityFireability.txt | cut -d ' ' -f 2 | sort -u) ; do
echo "FORMULA_NAME $x"
done
elif [ -f "ReachabilityFireability.xml" ] ; then # for cunf (txt files deleted;-)
echo echo "here is the order used to build the result vector(from xml file)"
for x in $(grep '' ReachabilityFireability.xml | cut -d '>' -f 2 | cut -d '<' -f 1 | sort -u) ; do
echo "FORMULA_NAME $x"
done
elif [ "ReachabilityFireability" = "ReachabilityDeadlock" ] || [ "ReachabilityFireability" = "QuasiLiveness" ] || [ "ReachabilityFireability" = "StableMarking" ] || [ "ReachabilityFireability" = "Liveness" ] || [ "ReachabilityFireability" = "OneSafe" ] ; then
echo "FORMULA_NAME ReachabilityFireability"
fi
echo
echo "=== Now, execution of the tool begins"
echo
echo -n "BK_START "
date -u +%s%3N
echo
timeout -s 9 $BK_TIME_CONFINEMENT bash -c "/home/mcc/BenchKit/BenchKit_head.sh 2> STDERR ; echo ; echo -n \"BK_STOP \" ; date -u +%s%3N"
if [ $? -eq 137 ] ; then
echo
echo "BK_TIME_CONFINEMENT_REACHED"
fi
echo
echo "--------------------"
echo "content from stderr:"
echo
cat STDERR ;